Lyoprester®

           LYOphilization                   PREcision                      STERility

Lyoprester SS™ — the ultimate pharmaceutical container for the single shot

The Lyoprester SS takes the dual-chamber Lyoprester architecture one decisive step further: a special top plunger that accommodates a syringe piston and a needle adaptor, turning the cartridge itself into a complete, self-contained injection system. The lyophilized active rests in its protected chamber as a dry cake — its most stable state — while the P-EARLs™ solvent waits in the second chamber, behind the internal septum. Nothing meets anything until the moment of use.

Ready for action, P-EARLs included: you just screw a needle, inject, then throw.

One action, aseptic by construction

Screwing the needle adaptor on and advancing the piston breaches the internal septum: the P-EARLs flows forward over the cake, the full dose reconstitutes inside the closed container in seconds, and the injection is delivered through the attached needle. There is no diluent vial to open, no syringe draw-up, no transfer step — and therefore no open contamination path anywhere between the shelf and the patient.

The advantages, gathered

• Aseptic reconstitution at the point of use — cake and solvent are kept apart by the septum until the single action that mixes them, inside a closed sterile container.
• Stability and long shelf life — the active is stored lyophilized, the state in which peptides, proteins and small molecules keep longest, isolated from the solvent until the moment of injection.
• Exact pre-filled dose — no measuring, no draw-up, no dosing error: the dose is set at manufacture, not at the bedside.
• Single shot — no preservative, no waste — no multi-dose vial means no antimicrobial preservative and nothing left over to discard or to degrade.
• Economical, low cost — a cartridge, a plunger and a needle adaptor: a fraction of the complexity and cost of prefilled syringes and autoinjectors.
• Built for high-load APIs — designed to carry heavy lyophilized loads, including Panacea’s multi-layer Peptourbillon™ cakes approaching 200 mg of actives, where a conventional vial reconstitution wets only the surface of the cake.
• Patient-simple — screw a needle, inject, throw. Minimal training, no reconstitution ritual, no sharps guesswork.
• Cold-chain forgiving — a dry cake tolerates temperature excursions far better than a finished solution.
• Standard geometry — cartridge format compatible with pen injectors such as Panacea’s EZnject™, and with standard luer needles.

What it can carry

Any injectable that benefits from being stored dry and reconstituted at the point of use: GLP-1 and multi-agonist peptide therapies, NAD+ and the redox coenzymes, glutathione, hormones, vaccines, insulin, enzymes and biologics, fertility treatments, B-vitamin complexes, emergency medicines such as adrenaline and naloxone, and veterinary single-dose products. Where the active is fragile in solution, heavy-loaded, or dosed exactly once — the Lyoprester SS is the container.

Lyoprester SS is Panacea Bio Chem’s answer to the last unsolved step of injectable medicine: everything that has to happen between the shelf and the patient.